Wacom Graphire Cte 440 Software
The Wacom Graphire 4 CTE-640 is quite an old model (over 10 years I think), so you can't really expect Wacom to continue updating drivers for newer versions of macOS. That said, have you tried using the driver for Mac OS X? This is the last official driver for your model and was released to support Mac OS X Mountain Lion 10.8. If not, it may be worth giving it a go (or, if you have, removing it and re-installing it). Potential workaround If installing the above driver doesn't seem to work, there's also a potential workaround that may get it to work.